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Impact of the COVID-19 pandemic on total, sex- and age-specific all-cause mortality in 20 countries worldwide during 2020: results from the C-MOR project.
Demetriou, Christiana A; Achilleos, Souzana; Quattrocchi, Annalisa; Gabel, John; Critselis, Elena; Constantinou, Constantina; Nicolaou, Nicoletta; Ambrosio, Giuseppe; Bennett, Catherine M; Le Meur, Nolwenn; Critchley, Julia A; Mortensen, Laust Hvas; Rodriguez-Llanes, Jose Manuel; Chong, Mario; Denissov, Gleb; Klepac, Petra; Goldsmith, Lucy P; Costa, Antonio José Leal; Hagen, Terje P; Chan Sun, Marie; Huang, Qian; Pidmurniak, Nataliia; Zucker, Inbar; Cuthbertson, Joseph; Burström, Bo; Barron, Manuel; Erzen, Ivan; Stracci, Fabrizio; Calmon, Wilson; Martial, Cyndy; Verstiuk, Olesia; Kaufman, Zalman; Tao, Wenjing; Kereselidze, Maia; Chikhladze, Nino; Polemitis, Antonis; Charalambous, Andreas.
Affiliation
  • Demetriou CA; Department of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.
  • Achilleos S; Department of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.
  • Quattrocchi A; Department of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.
  • Gabel J; University of Nicosia Medical School, Nicosia, Cyprus.
  • Critselis E; Department of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.
  • Constantinou C; Department of Basic and Clinical Sciences, University of Nicosia Medical School, Nicosia, Cyprus.
  • Nicolaou N; Department of Basic and Clinical Sciences, University of Nicosia Medical School, Nicosia, Cyprus.
  • Ambrosio G; Department of Medicine, University of Perugia School of Medicine, Perugia, Italy.
  • Bennett CM; Institute for Health Transformation, Deakin University, Burwood, Australia.
  • Le Meur N; University of Rennes, EHESP, CNRS, Inserm, Arènes-UMR 6051, RSMS-U 1309, Rennes, France.
  • Critchley JA; Population Health Research Institute, St George's, University of London, London, UK.
  • Mortensen LH; Department of Methods and Analysis, Statistics Denmark, Copenhagen Oe, Denmark.
  • Rodriguez-Llanes JM; European Commission Joint Research Centre, Ispra, VA, Italy.
  • Chong M; Departamento de Ingeniería, Universidad del Pacífico, Lima, Peru.
  • Denissov G; Estonian Causes of Death Registry, National institute for Health Development, Tallinn, Estonia.
  • Klepac P; Department of Communicable Diseases, National Institute of Public Health, Ljubljana, Slovenia.
  • Goldsmith LP; Institute for Infection and Immunity, and Population Health Research Institute, St George's, University of London, London, UK.
  • Costa AJL; Institute of Studies in Collective Health (IESC), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Hagen TP; Department of Health Management and Health Economics, Institute of Health and Society, University of Oslo, Oslo, Norway.
  • Chan Sun M; Department of Medicine, Faculty of Medicine and Health Sciences, University of Mauritius, Réduit, Mauritius.
  • Huang Q; Department of Geography, Center for Rural and Primary Healthcare, University of South Carolina, Columbia, SC, USA.
  • Pidmurniak N; Department of Medicine, Bogomolets National Medical University, Kyiv, Ukraine.
  • Zucker I; School of Public Health, Ministry of Health, Ramat Gan, Israel.
  • Cuthbertson J; Disaster Resilience Initiative, Monash University, Clayton,VIC, Australia.
  • Burström B; Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
  • Barron M; Department of Economics, Universidad del Pacifico Av Sanchez Cerro, Lima, Peru.
  • Erzen I; School of Public Health, National Institute of Public Health, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia.
  • Stracci F; Public Health Section, Department of Medicine and Surgery, University of Perugia, Piazza Lucio Severi, Perugia, Italy.
  • Calmon W; Institute of Mathematics and Statistics, Fluminense Federal University, Niteroi, Brazil.
  • Martial C; Department of Demography, Statistics Mauritius, LIC Centre, Port Louis, Mauritius.
  • Verstiuk O; University of Nicosia Medical School, Nicosia, Cyprus.
  • Kaufman Z; Israeli Center of Disease Control, Ministry of Health, Ramat Gan, Israel.
  • Tao W; Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
  • Kereselidze M; Department of Molecular Medicine and SURGERY, Karolinska Institutet, Stockholm, Sweden.
  • Chikhladze N; National Center for Disease Control and Public Health, Tbilisi, Georgia.
  • Polemitis A; Faculty of Medicine, Ivane Javakhishvili Tbilisi State University, Tbilisi, Georgia.
  • Charalambous A; University of Nicosia, Nicosia, Cyprus.
Int J Epidemiol ; 52(3): 664-676, 2023 06 06.
Article in En | MEDLINE | ID: mdl-36029524
BACKGROUND: To understand the impact of the COVID-19 pandemic on mortality, this study investigates overall, sex- and age-specific excess all-cause mortality in 20 countries, during 2020. METHODS: Total, sex- and age-specific weekly all-cause mortality for 2015-2020 was collected from national vital statistics databases. Excess mortality for 2020 was calculated by comparing weekly 2020 observed mortality against expected mortality, estimated from historical data (2015-2019) accounting for seasonality, long- and short-term trends. Crude and age-standardized rates were analysed for total and sex-specific mortality. RESULTS: Austria, Brazil, Cyprus, England and Wales, France, Georgia, Israel, Italy, Northern Ireland, Peru, Scotland, Slovenia, Sweden, and the USA displayed substantial excess age-standardized mortality of varying duration during 2020, while Australia, Denmark, Estonia, Mauritius, Norway, and Ukraine did not. In sex-specific analyses, excess mortality was higher in males than females, except for Slovenia (higher in females) and Cyprus (similar in both sexes). Lastly, for most countries substantial excess mortality was only detectable (Austria, Cyprus, Israel, and Slovenia) or was higher (Brazil, England and Wales, France, Georgia, Italy, Northern Ireland, Sweden, Peru and the USA) in the oldest age group investigated. Peru demonstrated substantial excess mortality even in the <45 age group. CONCLUSIONS: This study highlights that excess all-cause mortality during 2020 is context dependent, with specific countries, sex- and age-groups being most affected. As the pandemic continues, tracking excess mortality is important to accurately estimate the true toll of COVID-19, while at the same time investigating the effects of changing contexts, different variants, testing, quarantine, and vaccination strategies.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: COVID-19 Limits: Female / Humans / Male Country/Region as subject: Europa Language: En Journal: Int J Epidemiol Year: 2023 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: COVID-19 Limits: Female / Humans / Male Country/Region as subject: Europa Language: En Journal: Int J Epidemiol Year: 2023 Document type: Article Affiliation country: Country of publication: